Paediatric European network treatment AIDS and European collaborative study on HIV-infected pregnant women and their children

The ECS network includes >25 centers in 11 countries and included >6300 mother-child pairs by June 2005. PENTA aims to strengthen and extend the evidence base for the clinical management of HIV infected children through an integrated programme of CTs and studies. Workplans include design, co-ordination and analysis of CTs and substudies to optimize antiretroviral therapy (ART) use; to enhance knowledge of HIV pathogenesis in children and improve the standard of care for infected children across Europe by encouraging collaboration between paediatricians, and providing an accredited training programme.